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These symptoms may indicate medication intolerance, underlying gastrointestinal conditions unrelated to tirzepatide, or need for dose adjustment rather than continued escalation
Raun K, von Voss P, Gotfredsen CF, Golozoubova V, Rolin B, Knudsen LB
The confusion comes from misreading the SURPASS-2 trial (Fras et al., New England Journal of Medicine 2021), which compared tirzepatide to semaglutide 1 mg in type 2 diabetes patients
In conclusion, superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels may play an important role in the etiopathogenesis of refractory epilepsy
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